The 2025 college football season is now six weeks in, and the Big 12 seems to be establishing a four-team upper tier, with Texas Tech emerging as the team to beat. Those programs included Iowa State, Arizona State, BYU and Cincinnati. Utah, Kansas, TCU and Baylor are just below that upper echelon. The Week 7 Big 12 slate features one matchup that could decide who plays Texas Tech in the Big 12 title game.
Every week, our staff gathers to pick every Big 12 football game. It is a challenging task, especially considering the conference’s crowded nature. It remains to be seen whether one of the teams mentioned will pull away and become the team to beat, as is often the case in the Big 12; the title race is still very much up for grabs.
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So, how will Week 7 play out in the Big 12? We have only seven games on the schedule, one of the conference’s lighter weekends of the season. Our Buffaloes Wire staff picked all seven games in the conference straight up.
Here are our expert picks for Week 7. But first, here are the standings so far from our writers through five weeks.
All games are scheduled for Saturday, October 11, unless otherwise noted, and all times are Mountain Time.
Standings so far
Charlie Strella: 52-12
Jack Freeman: 48-17
Griffin Dreifaldt: 52-12
Cincinnati Bearcats quarterback Brendan Sorsby (2) celebrates with teammates in the second quarter of the NCAA football game between the Cincinnati Bearcats and Iowa State Cyclones at Nippert Stadium in Cincinnati on Oct. 4, 2025.
10:00 a.m., FS1
Griffin: Cincinnati
Cincinnati takes care of business with a dominant win over UCF. The Bearcats continue to prove they’re a legitimate threat in the Big 12 and show no signs of slowing down.
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Jack: Cincinnati
Charlie: Cincinnati
Oklahoma State vs. Houston
Players take the field before an NCAA football game between Oklahoma State (OSU) and UT Martin in Stillwater, Okla., on Thursday, Aug. 28, 2025.
10:00 a.m., TNT
Griffin: Houston
Jack: Houston
Charlie: Houston
Iowa State Cyclones’ defensive line Vontroy Malone (8), linebacker Cael Brezina (9), and defensive back Drew Surges (29) celebrates after a stop South Dakota during the second quarter in the home game opening at Jack Trice Stadium on August 30, 2025, in Ames, Iowa
1:30 p.m., ESPN
We will share our Colorado-Iowa State predictions in a separate post, where each staff member will provide a final score prediction and offer some thoughts. Colorado is hoping to make a rebound after back-to-back tough losses.
Oct 4, 2025; Fort Worth, Texas, USA; TCU Horned Frogs quarterback Josh Hoover (10) stands in the pocket against the Colorado Buffaloes during the first half at Amon G. Carter Stadium. Mandatory Credit: Raymond Carlin III-Imagn Images
1:30 p.m., Fox
Griffin: TCU
Jack: TCU
TCU looked unstoppable against Colorado, with Josh Hoover dotting up the Buffaloes’ defense en route to a 35-21 victory, and I see a very similar result this week. Kansas State’s defense couldn’t stop a fly last week against Baylor, and the offense will be without its best player, running back Dylan Edwards, yet again. It seems like the Wildcats cannot catch a break in 2025, as they show flashes but ultimately fail to live up to their potential. Meanwhile, the Horned Frogs have Big 12 title ambitions and play like it.
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Charlie: Kansas State
Kansas State not having running back Dylan Edwards will definitely hurt, but the game is in Manhattan, Kansas, which is more important. The Wildcats are starting to turn a corner, and I think they complete that turn around this weekend against TCU.
No. 10 Texas Tech vs. Kansas
Texas Tech’s Behren Morton prepares to throw against Arkansas-Pine Bluff during a non-conference football game, Saturday, August 30, 2025, at Jones AT&T Stadium.
5:30 p.m., Fox
Griffin: Texas Tech
Texas Tech beats Kansas on the road. The Red Raiders become the first team to finally contain Jalon Daniels and the Jayhawks’ high-powered offense, walking out of Lawrence with an impressive win.
Jack: Texas Tech
Charlie: Texas Tech
I like Kansas to cover the two-touchdown spread, but the Red Raiders are a top-10 team for a reason, and I expect them to continue to show that, especially at home.
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Sep 12, 2025; Tucson, Arizona, USA; Arizona Wildcats defensive back Gavin Hunter (23) celebrates with teammate during the fourth quarter against the Kansas State Wildcats at Arizona Stadium. Mandatory Credit: Aryanna Frank-Imagn Images
6:00 p.m., ESPN2
Griffin: BYU
Jack: BYU
Charlie: BYU
Arizona is a much-improved squad, but BYU can contend for the Big 12 title, and the Wildcats aren’t on that level quite yet. I do think this game remains close, but the Cougars have enough to pull away late.
Sep 6, 2025; Salt Lake City, Utah, USA; Utah Utes running back Wayshawn Parker (1) runs for a touchdown against the Cal Poly Mustangs during the second half at Rice-Eccles Stadium. Mandatory Credit: Rob Gray-Imagn Images
8:15 p.m., ESPN
Griffin: Arizona State
Arizona State pulls off the upset in Salt Lake City. We saw what happened when Utah faced a real offense in Texas Tech — they struggled big time. The Sun Devils pick up where the Red Raiders left off, lighting up the scoreboard in a high-scoring Big 12 classic under the lights.
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Jack: Utah
Depending on what versions of these two teams show up, we could be in for one of the greatest Big 12 Conference games of the season or a snoozefest where both offenses manage to snatch failure from the jaws of success. Arizona State hasn’t had the explosive offense that you’d expect from Sam Leavitt and Jordyn Tyson, yet, they’ve managed several close wins over quality Big 12 opponents. Utah is a boom-or-bust team that depends on its quarterback, Devon Dampier, to get things rolling. As a noted fan of Dampier’s play, I’m picking Utah because I believe he’s found his stride for the Utes.
Charlie: Utah
I might have gone initially with Arizona State on the road, but with Sun Devils’ quarterback Sam Leavitt listed as doubtful for Saturday night’s contest, the outlook changes drastically. Utah has a prolific offense led by Devon Dampier, and Rice-Eccles will be fired up Saturday night. Give me the Utes.
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This article originally appeared on Buffaloes Wire: Big 12 predictions, picks for college football Week 7
