Orioles at Phillies Prediction: Odds, expert picks, starting pitchers, betting trends and stats for August 6

Its Wednesday, August 6 and the Orioles (51-63) are in Philadelphia this afternoon looking to avoid being swept by the Phillies (65-48).

Trevor Rogers is slated to take the mound for Baltimore against Ranger Suárez for Philadelphia.

Taijuan Walker and three relievers struck out ten and limited the Orioles to five hits enroute to a 5-0 win Tuesday night. Brandon Marsh went yard and drove in a pair of runs to pace the attack. The Phillies now lead the National League East by 2.5 games.

Lets dive into today’s matchup and find a sweat or two.

We’ve got all the info and analysis you need to know ahead of the game, including the latest info on the how to catch today’s first pitch, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.

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Game details & how to watch Orioles at Phillies

• Date: Wednesday, August 6, 2025
• Time: 12:35PM EST
• Site: Citizens Bank Park
• City: Philadelphia, PA
• Network/Streaming: MASN, NBCSP

Never miss a second of the action and stay up-to-date with all the latest team stats and player news. Check out our day-by-day MLB schedule page, along with detailed matchup pages that update live in-game with every out.

Odds for the Orioles at the Phillies

The latest odds as of Wednesday:

• Moneyline: Orioles (+136), Phillies (-162)
• Spread: Phillies -1.5
• Total: 8.0 runs

Probable starting pitchers for Orioles at Phillies

• Pitching matchup for August 6, 2025: Trevor Rogers vs. Ranger Suárez
  • Orioles: Trevor Rogers (4-2, 1.44 ERA)
    Last outing: August 1 at Cubs – 1.13 ERA, 1 Earned Runs Allowed, 4 Hits Allowed, 0 Walks, and 8 Strikeouts
  • Phillies: Ranger Suárez (8-4, 2.68 ERA)
    Last outing: August 1 vs. Detroit – 3.86 ERA, 3 Earned Runs Allowed, 4 Hits Allowed, 0 Walks, and 5 Strikeouts

Rotoworld still has you covered with all the latest MLB player news for all 30 teams. Check out the feed page right here on NBC Sports for headlines, injuries and transactions where you can filter by league, team, positions and news type!

Top betting trends & insights to know ahead of Orioles at Phillies

• The Phillies are 65-48 (.575) this season and 10-6 (.625) with Ranger Suarez on the mound
• The Phillies’ last 3 games have gone over the Total when Ranger Suarez takes the mound
• Betting the Phillies on the Run Line with Ranger Suarez starting would have returned a 1.89-unit profit in 2025
• Nick Castellanos is riding a 6-game hitting streak (7-21)

If you’re looking for more key trends and stats around the spread, moneyline and total for every single game on the schedule today, check out our MLB Top Trends tool on NBC Sports!

Expert picks & predictions for today’s game between the Orioles and the Phillies

Rotoworld Best Bet

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Our model calculates projections around each moneyline, spread and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information and weather forecasts.

Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.

Here are the best bets our model is projecting for Wednesday’s game between the Orioles and the Phillies:

• Moneyline: NBC Sports Bet is recommending a play on the Philadelphia Phillies on the Moneyline.
• Spread: NBC Sports Bet is leaning towards a play ATS on the Baltimore Orioles at +1.5.
• Total: NBC Sports Bet is leaning towards a play on the over on the Game Total of 8.0.

Want even more MLB best bets and predictions from our expert staff & tools? Check out the Expert MLB Predictions page from NBC

Follow our experts on socials to keep up with all the latest content from the staff:

• Jay Croucher (@croucherJD)
• Drew Dinsick (@whale_capper)
• Vaughn Dalzell (@VmoneySports)
• Brad Thomas (@MrBradThomas)